Table 1.

Characteristics of the LS cohort (112 Finnish females with a path_MMR variant)

	Whole LS cohort (N = 112)	Study population (responders) (N = 76)
Age
Median (range)	49 (30–89)	52 (30–82)
Age at mutation testing
Median	38 (20–72)	36 (22–65)
Distribution of MMR genes
MLH1	72 (64%)	47 (62%)
MSH2	32 (29%)	22 (29%)
MSH6	8 (7%)	7 (9%)
History of other cancer (Y/N)
Y	42 (38%)	24 (33%)
N	70 (62%)	49 (67%)
Prophylactic surgery performed
Y	63 (56%)	42 (68%)
N	49 (44%)	24 (32%)

LS Lynch syndrome, path_MMR pathogenic variant of DNA mismatch repair gene