Table 3.
Clinical, genetic and pathological characteristics of seven MAP patients with Barrett’s esophagus
| Patient | Sex | Age at diagnosis (years) | Mutation 1 | Mutation 2 | Initial PA report | Revision |
|---|---|---|---|---|---|---|
| 1 | F | 61 | c.536A>G p.(Tyr179Cys) | c.638C>T p.(Pro213Leu) | No dysplasia | No dysplasia |
| 2 | M | 72 | c.1147delC, p.(Glu369Argfs*39) | c.1214C>T p.(Pro405Leu) | High grade dysplasia | High grade dysplasia |
| 3 | F | 54 | c.1187G>A p.(Gly396Asp) | c.1214C>T p.(Pro405Leu) | Low grade dysplasia | No dysplasia |
| 4 | M | 58 | c.536A>G p.(Tyr179Cys) | c.536A>G p.(Tyr179Cys) | Low grade dysplasia | Not available |
| 5 | M | 57 | c.536A>G p.(Tyr179Cys) | c.1214C>T p.(Pro405Leu) | No dysplasia | Indefinite for dysplasia |
| 6 | M | 55 | c.536A>G p.(Tyr179Cys) | c.933 + 3A >C splice site intron 10 | No dysplasia | Indefinite for dysplasia |
| 7 | M | 65 | c.536A>G p.(Tyr179Cys) | c.1187G>A p.(Gly396Asp) | No dysplasia | No dysplasia |