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. 2020 Mar 27;10:5569. doi: 10.1038/s41598-020-62501-1

Table 3.

IC50 of DTX formulated in Taxotere and nanoliposomes on NIH/3T3, 4T1, TUBO, and MCF-7 cells after 24, 48 and 72 hour cell culture at the same DTX dose (n = 6, mean ± SD).

Cell Lines Incubation Time (hour) IC50 (ug/ml)
NIH 24 Taxotere F1 F2 F3
27.01 128.83 77.96 26.13
48 27.73 22.77 32.95 11.5
72 26.7 13.42 12.15 5.7
4T1 24 53.27 304.96 154.5 67.44
48 12.39 40.15 27.27 20.9
72 13 8.7 14.13 14
TUBO 24 17.5 223.5 153 9.5
48 14.32 39.63 17.8 0.84
72 4.7 4.1 0.5 0.0312
MCF-7 24 48.35 167.72 170.88 22.99
48 24 10.75 24.98 18.11
72 14.35 1.9 15.9 6.7