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. 2020 Mar 27;10:5605. doi: 10.1038/s41598-020-62391-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Risk of (A) Major Coronary Events, (B) Ischemic Stroke, and (C) Intracerebral hemorrhage per standard deviation (SD) of usual log-transformed high-sensitivity C-reactive protein (CRP). Models were adjusted for age, age² and sex (base model) and additionally for income, occupation, education, SBP, BMI, diabetes, physical activity, standing height, smoking, alcohol, LDL-C and TG (Full model). The models were fitted separately for each of the 10 study areas and estimates were meta-analyzed. Error bars represent 95% confidence intervals (CI). The areas of the boxes are proportional to the inverse of the variance of the log ORs.