Table 1.
Baseline traits of study participants.
| Trait | Controls (n = 5285) | Major Coronary Events (n = 1508) | Ischemic Stroke (n = 5418) | Intracerebral Hemorrhage (n = 4476) | ||||
|---|---|---|---|---|---|---|---|---|
| Age and Sociodemographic factors | ||||||||
| Age, y* | 55.8 (10.9) | 56.5 (9.72) | 55.4 (9.36) | 59.3 (10.1) | ||||
| Female†, % | 49.6 | 41.6 | 55.6 | 49.9 | ||||
| Rural‡, % | 79.2 | 66.6 | 54.6 | 79.5 | ||||
| Middle School and above, % | 38.3 | 36.8 | 38.2 | 36.0 | ||||
| Income > 10,000 yuan/year, % | 62.2 | 61.5 | 65.6 | 62.5 | ||||
| Lifestyle factors | ||||||||
| Male smokers, % | 87.1 | 90.9 | 89.5 | 86.9 | ||||
| Female smokers, % | 3.9 | 7.8 | 5.4 | 5.9 | ||||
| Male regular drinkers, % | 32.1 | 26.5 | 30.9 | 33.1 | ||||
| Female regular drinkers, % | 2.1 | 1.8 | 2.2 | 2.1 | ||||
| Physical activity, MET h/day | 20.1 (11.8) | 18.7 (11.6) | 18.7 (11.5) | 19.0 (11.6) | ||||
| Anthropometric, blood pressure and circulatory measures | ||||||||
| Standing height, m | 1.59 (0.06) | 1.59 (0.06) | 1.59 (0.06) | 1.58 (0.06) | ||||
| BMI, kg/m2 | 23.4 (3.1) | 23.9 (3.4) | 24.1 (3.4) | 23.8 (3.4) | ||||
| Waist-hip ratio | 0.89 (0.07) | 0.91 (0.07) | 0.90 (0.07) | 0.90 (0.07) | ||||
| SBP, mmHg | 134.4 (19.7) | 143.6 (25.1) | 144.4 (23.9) | 152.9 (27.3) | ||||
| DBP, mmHg | 78.5 (11.0) | 83.0 (13.3) | 83.9 (12.5) | 88.5 (14.2) | ||||
| Heart rate, per minute | 78.3 (11.7) | 80.4 (12.7) | 79.2 (12.1) | 79.9 (12.6) | ||||
| Markers of subclinical atherosclerosis | ||||||||
| Plaque, % | 39.9 | 60.5 | 50.7 | 44.4 | ||||
| cIMT, mm | 0.71 (0.13) | 0.78 (0.23) | 0.75 (0.16) | 0.72 (0.16) | ||||
| Inflammatory biomarkers | ||||||||
| CRP, mg/L§ | 0.90 (0.86–0.93) | 1.31 (1.24–1.39) | 1.12 (1.08–1.16) | 1.08 (1.04–1.13) | ||||
| Fibrinogen, g/L§ | 3.00 (2.98–3.03) | 3.07 (3.04–3.11) | 3.05 (3.02–3.08) | 3.02 (2.99–3.05) | ||||
| Lipids | ||||||||
| Triglycerides§, mg/dL | 145.8 (143.1–148.5) | 163.4 (158.5–168.5) | 156.6 (153.9–159.45) | 145.5 (142.7–148.5) | ||||
| LDL cholesterol?, mg/dL | 91.6 (23.9) | 95.9 (29.1) | 95.9 (25.8) | 90.8 (26.4) | ||||
| Self-reported health and disease | ||||||||
| Poor self-rated health, % | 8.1 | 18.4 | 14.6 | 15.5 | ||||
| Hypertension, % | 10.4 | 21.7 | 23.7 | 26.4 | ||||
| Diabetes, % | 6.0 | 14.0 | 12.4 | 9.3 | ||||
CRP: C-reactive protein; cIMT: carotid intima-media thickness; DBP: Diastolic Blood Pressure; ICH: Intracerebral hemorrhage; IS: Ischemic stroke; LDL: Low-density lipoprotein; MET: metabolic equivalents; SBP: Systolic Blood Pressure.
Values are mean (standard deviation) for continuous traits or proportion (weighted percentage) for binary/categorical traits, standardized to age, sex and study area of case-control cohort unless otherwise stated.
*Standardized to sex and study area only.
†Standardized to age and study area only.
‡Standardized to age and sex only.
§Geometric mean (95% CI). ?Note: Low-density lipoprotein (LDL) cholesterol was directly measured.