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. 2020 Mar 27;10:5581. doi: 10.1038/s41598-020-62621-8

Figure 2.

Figure 2

Discovery of SMPD1 targeting miRs that are differentially regulated by radiation. (A) TargetScan prediction of miR candidates that harbor binding sites on the 3′ untranslated region of human SMPD1. (B) miR candidates targeting SMPD1 exhibit radiation dose-dependent differential expression at 6 h post-IR in HUVECs. Fold changes vs control untreated cells are indicated in colored cells relative to expression of the respective miRNA in non-irradiated samples. Red = increased expression. blue = decreased expression.