Table 1.
Demographics and clinical characteristics of included subjects.
| Control (n = 39) | POAG (n = 32) | PACG (n = 30) | p* | p** | p*** | |
|---|---|---|---|---|---|---|
| Age (years) | 69.08 ± 5.03 | 67.16 ± 6.04 | 70.47 ± 5.66 | 0.329 | 0.542 | 0.075 |
| Sex (male/female) | 14/25 | 19/13 | 3/27 | 0.059 | 0.023 | 0.000 |
| Hypertension, % (n) | 41.03% | 62.50% | 36.67% | 0.096 | 0.806 | 0.074 |
| Cardiovascular disease, % (n) | 12.82% | 29.03% | 16.67% | 0.133 | 0.737 | 0.363 |
| SBP (mmHg) | 138.29 ± 19.54 | 142.65 ± 20.11 | 132.65 ± 21.45 | 0.758 | 0.599 | 0.298 |
| DBP (mmHg) | 81.64 ± 15.18 | 82.88 ± 16.63 | 70.91 ± 15.29 | 0.966 | 0.041 | 0.066 |
| BCVA | 0.86 ± 0.13 | 0.82 ± 0.20 | 0.77 ± 0.22 | 0.537 | 0.105 | 0.631 |
| SE (D) | 0.49 ± 1.67 | −0.96 ± 2.30 | 0.38 ± 2.41 | 0.016 | 0.977 | 0.093 |
| IOP (mmHg) | 15.77 ± 3.50 | 16.23 ± 3.07 | 16.03 ± 3.61 | 0.831 | 0.950 | 0.973 |
| CCT (μm) | 541.48 ± 32.96 | 555.32 ± 26.74 | 551.21 ± 35.62 | 0.261 | 0.586 | 0.897 |
| Glaucoma eyedrops (n) | 0.23 ± 0.48 | 1.41 ± 0.98 | 1.20 ± 0.96 | 0.000 | 0.000 | 0.682 |
| Visual field index (%) | 96.33 ± 7.87 | 88.06 ± 9.79 | 91.43 ± 6.43 | 0.001 | 0.016 | 0.249 |
| Visual field MD (dB) | −0.16 ± 3.33 | −4.31 ± 3.46 | −4.46 ± 3.37 | 0.000 | 0.000 | 0.982 |
| Visual field PSD (dB) | 2.21 ± 1.96 | 5.67 ± 3.52 | 4.00 ± 2.25 | 0.000 | 0.003 | 0.075 |
Values are presented as mean ± standard deviation unless otherwise indicated. *Comparison between the control and POAG groups. **Comparison between the control and PACG groups. ***Comparison between the POAG and PACG groups. BCVA, best-corrected visual acuity; CCT, central corneal thickness; dB, decibel; DBP, diastolic blood pressure; IOP, intraocular pressure; MD, mean deviation; PACG, primary angle-closure glaucoma; POAG, primary open-angle glaucoma; PSD, pattern standard deviation; SBP, systolic blood pressure; SE, spherical equivalence.