Table 3. Characteristics and Antibody Titer of Convalescent Plasma Donors.
Donorsa | |||||
---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | |
Blood type | B | B | B | A | B |
Donated plasma volume, mL | 400 | 400 | 400 | 400 | 400 |
Interval between symptom onset and discharge, d | 11 | 11 | 13 | 13 | 11 |
Interval between discharge and plasma donation, d | 11 | 11 | 13 | 11 | 12 |
RBD-specific IgG ELISA titerb | 16 200 | 1800 | 1800 | 5400 | 16 200 |
RBD-specific IgM ELISA titerc | 16 200 | 1800 | 5400 | 5400 | 5400 |
Neutralizing antibody titerd | 240 | 80 | 120 | 240 | 480 |
Abbreviation: RBD, receptor binding domain.
Donors-patients were matched by number (donor 1 gave plasma to patient 1, etc).
ELISA end point dilution titers (IgG antibody). The expected titer of negative control from a healthy person is ≤200.
ELISA end point dilution titers (IgM antibody). The expected titer of negative control from a healthy person is ≤200.
Neutralization end point dilution titers. The expected titer of negative control from a healthy person is ≤10.