. 2010 Jun 30;38(5):401–405. doi: 10.1007/s15010-010-0036-x

Table 2.

Subgroup analyses (statistically significant results only, except)

Subgroup	Variable	Results	Significance (P)
HSV-1-positive patients vs. HSV-negative patients
>60 years old (n = 22 and 21)	Day of mechanical ventilation	10 vs. 1	0.01^a
>60 years old (n = 18 and 17)	PEEP	12 vs. 8	0.01^a
ARDS (n = 37 and 31)	Day of mechanical ventilation	8 vs. 1	0.001^b
	Tracheobronchitis	21 vs. 31	0.001^b
	Renal insufficiency	19 vs. 26	0.005^b
CMV-positivity (n = 10 and 5)	ARDS	4 vs. 5	0.04^a
Without bacterial pathogen (n = 36 and 32)	Days of mechanical ventilation	8 vs. 1	0.004^a
Without bacterial pathogen (n = 36 and 32)	Tracheobronchitis	22/36 vs. 27/32	0.03^b
HSV-positive patients
Immunocompetent vs. Immunocompromised	Elevation of transaminases	8/12 vs. 10/33	0.04^b
Aciclovir vs. no antiviral treatment (n = 25 vs. 26)	Viral load (geq/ml)	1.5E+05 vs. 6.5E+03	0.03^a
	CMV positivity	1/24 vs. 10/26	0.005^b
	Interstitial pneumonia (X-ray)	7/25 vs. 1/26	0.02^a
	Mortality^c	9/25 vs. 14/26^c	0.26^c
Viral load >10E+05 vs. <10E+05 geq/ml (n = 21 vs. 29)	Length of ICU stay (days)	25 vs. 13	0.04^a
	Mechanical ventilation	20/21 vs. 17/29	0.004^b
	ARDS	19/21 vs. 18/29	0.005^b
	Sepsis	18/21 vs. 14/29	0.008^b
	Detection of bacterial pathogens	10/21 vs. 4/29	0.01^b

^aWilcoxon rank sum test

^bFisher exact test

^cNot significant