Recommendation

35. For mechanically ventilated adults with COVID-19 and moderate to severe ARDS:

35.1. (NMBA), over continuous NMBA infusion, to facilitate protective lung ventilation. Weak recommendation, low-quality evidence.

35.2. In the event of persistent ventilator dyssynchrony, the need for ongoing deep sedation, prone ventilation, or persistently high plateau pressures, we suggest using a continuous NMBA infusion for up to 48 h. Weak recommendation, low-quality evidence.