Recommendations

23. In adults with COVID-19, we suggest starting supplemental oxygen if the peripheral oxygen saturation (SpO2) is < 92% (weak recommendation, low-quality evidence), and recommend starting supplemental oxygen if SpO2 is < 90%. Strong recommendation, moderate quality evidence.

24. In adults with COVID-19 and acute hypoxemic respiratory failure on oxygen, we recommend that SpO2 be maintained no higher than 96%. Strong recommendation, moderate quality evidence.