Table 1.
Demographic features of the experimental dogs
| Sham (n = 7) | AF-Control (n = 7) | Ad-EGFP (n = 7) | Ad-ACE2 (n = 7) | p value△ | |
|---|---|---|---|---|---|
| Male | 4 | 3 | 5 | 4 | 0.876 |
| SPAF | 0 | 2 | 3 | 0 | 0.245 |
| Weight (kg) | 23.7 ± 3.4 | 24.2 ± 1.4 | 23.3 ± 2.4 | 23.8 ± 3.4 | 0.957 |
| Heart rate (beat/min) | |||||
| Baseline | 150 ± 5 | 152 ± 6 | 154 ± 7 | 155 ± 8 | 0.633 |
| 3 weeks | 151 ± 4 | 167 ± 4* | 166 ± 7# | 161 ± 5 | <0.001 |
| Temperature (°C) | |||||
| Baseline | 38.3 ± 0.4 | 38.3 ± 0.5 | 38.2 ± 0.4 | 38.2 ± 0.4 | 0.930 |
| 3 weeks | 38.4 ± 0.4 | 38.3 ± 0.5 | 38.3 ± 0.5 | 38.1 ± 0.5 | 0.779 |
△The p value of one-way ANOVA comparing the four groups.; baseline vs. 3 weeks: * p = 0.002; # p = 0.019, n = 7
SPAF spontaneous paroxysmal atrial fibrillation in each group