Table 11.
Sham | AF-Control | Ad-EGFP | Ad-ACE2 | *p | #p | ♂p | |
---|---|---|---|---|---|---|---|
Connexin 40 | 0.24 ± 0.05 | 0.39 ± 0.14 | 0.38 ± 0.13 | 0.19 ± 0.16 | 0.011 | 0.018 | <0.01 |
Connexin 43 | 1.16 ± 0.49 | 0.61 ± 0.39 | 0.58 ± 0.30 | 1.12 ± 0.57 | 0.031 | 0.022 | 0.044/0.031 |
Kv 4.2 protein | 1.56 ± 0.09 | 0.49 ± 0.03 | 0.50 ± 0.02 | 1.51 ± 0.12 | <0.001 | <0.001 | <0.001 |
Kv 4.3 protein | 1.47 ± 0.10 | 0.61 ± 0.09 | 0.50 ± 0.07 | 1.49 ± 0.12 | <0.001 | <0.001 | <0.001 |
L-type Ca++ CP α1C | 3.20 ± 0.27 | 1.47 ± 0.23 | 1.54 ± 0.15 | 1.65 ± 0.19 | <0.001 | <0.001 | <0.001& |
* Sham vs. AF-Control; * Sham vs. Ad-EGFP; ♂ Ad-ACE2 vs. Ad-EGFP (or AF-control); & Ad-ACE2 vs. Sham, n = 7