Table 3.
Changes in inducibility and duration of AF before and after gene transfer
| AF cases | AF times | AF inducibility (%) | Mean AF duration (s) | |
|---|---|---|---|---|
| Sham | ||||
| Baseline | 2 (28.6 %) | 6 | 28.6 | 35.1 ± 62.8 |
| 3 weeks | 3 (42.9 %) | 9 | 42.9 | 66.7 ± 86.1 |
| AF-control | ||||
| Baseline | 2 (28.6 %) | 19 | 28.6 | 274.4 ± 213.9 |
| 3 weeks | 7 (100 %) | 9 | 100 | 850.1 ± 225.2* |
| Ad-EGFP | ||||
| Baseline | 4 (57.1 %) | 20 | 57.1 | 227.3 ± 226.8 |
| 3 weeks | 7 (100 %) | 10 | 100 | 944.6 ± 256.0* |
| Ad-ACE2 | ||||
| Baseline | 4 (57.1 %) | 15 | 57.1 | 192.6 ± 190.6 |
| 3 weeks | 3 (42.9 %) | 13 | 42.9 | 89.1 ± 92.3**,# |
AF cases, the number of dogs having spontaneous or induced AF by procedure stimulation; AF times, the times of induced AF by procedure stimulation
* Compared with baseline and sham dogs: p < 0.01
** Compared with baseline: p = 0.097
#Compared with Ad-EGFP and control: p < 0.01