Table I.

Inhibition of QFS cleavage by the ACE2 inhibitor MLN-4760 (100 nM) and the competitive substrate angiotensin II (Ang II), in both supernatant and pellet fractions following ultracentrifugation of six individual human urine samples

Sample #	Inhibition of ACE2 QFS cleavage (%)
	MLN	5 μM Ang II	10 μM Ang II	20 μM Ang II	MLN + 20 μM Ang II
Urine supernatant
1	100	72	86	92	100
2	64	61	61	67	75
3	52	51	48	52	58
4	66	59	64	64	74
5	100	75	81	90	100
6	100	64	76	88	100
Urine pellet
1	100	76	87	93	96
2	93	73	86	89	91
3	74	60	64	66	77
4	89	68	77	84	88
5	97	67	73	83	97
6	95	67	78	86	100