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. 2018 Jun 16;41(4):1557–1567. doi: 10.1007/s10753-018-0802-y

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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Fig. 5 — Negative regulation of SOCS-1 on smoke-induced NALP3 inflammasome assembly, caspase-1 activation, and IL-1β expression. Ad-GFP or Ad-SOCS-1-treated mice were exposed to smoke for 15 min and allowed to rest for 1 day. Isolated alveolar macrophages were analyzed for a NALP3 inflammasome assembly and b caspase-1 activity and IL-1β secretion.