Table 2.
Effects of risk factors on acute renal failure following OLT by univariate analysis
| Variables | Total | Odds ratio (95 % CI) | p value |
|---|---|---|---|
| Etiology, n (%) | |||
| Others | 12 (3.1 %) | 0.74 (0.093, 6.0) | 0.780 |
| Fulminant hepatic failure | 30 (7.7) | 0.28 (0.037, 2.1) | 0.221 |
| Carcinoma | 81 (20.8) | 1.4 (0.69, 2.9) | 0.341 |
| Cirrhosis | 266 (68.4) | 1 | |
| ABO blood group, n (%) | |||
| Compatible | 334 (85.9) | 0.37 (0.18, 0.77) | 0.008* |
| Incompatibility | 55 (14.1) | 1 | |
| Child-Pugh grade, n (%) | |||
| Grade C | 302 (77.6) | 0.94 (0.45, 2.0) | 0.882 |
| Grade A/B | 87 (22.4) | 1 | |
| Blood loss, mean (SD), 500 ml | 6.9 (4.8) | 1.1 (1.0, 1.1) | 0.008* |
| Transfusion of blood products | |||
| Whole blood, mean (SD), U | 1.6 (3.7) | 1.0 (0.97, 1.1) | 0.277 |
| Red blood cells, mean (SD), U | 9.9 (7.1) | 1.0 (0.98, 1.1) | 0.384 |
| Fresh frozen plasma, mean (SD), U | 1.7 (4.0) | 0.99 (0.9, 1.1) | 0.804 |
| Platelet, mean (SD), U | 0.6 (1.0) | 0.92 (0.65, 1.3) | 0.628 |
| Cryoprecipitate, mean (SD), U | 5.2 (7.9) | 1.1 (1.0, 1,1) | 0.002* |
| Cell saver, mean (SD), ml | 554 (1,283) | 1.0 (1.0, 1.0) | 0.561 |
| Immunosuppressive protocol, n (%) | |||
| Including cyclosporine A | 107 (27.5) | 1.0 (0.51, 2.0) | 0.950 |
| Including FK506 | 273 (70.2) | 1 | |
| Steroid, n (%) | |||
| Used after OLT | 337 (86.6) | 3.5 (0.81, 14.8) | 0.093 |
| Not used after OLT | 52 (13.4) | 1 | |
| Infections, n (%) | |||
| Occurred before ARF | 55 (14.1) | 3.1 (1.5, 6.5) | 0.002* |
| Did not occur or occurred after ARF | 334 (85.9) | 1 | |
Intraoperative cryoprecipitate transfusion, ABO blood group compatibility, blood loss and infections occurring before ARF might be possible risk factors for ARF following OLT
* p <0. 05 indicates a crude association between variables and ARF following OLT