. Author manuscript; available in PMC: 2020 Mar 28.

Published in final edited form as: J Am Chem Soc. 2020 Jan 24;142(10):4793–4799. doi: 10.1021/jacs.9b13757

Table 1.

Substrate Scope of the Nickel-Hydride-Catalyzed Hydrodefluorination of Trifluoromethyl-Substituted Alkenes^a

Isolated yields, unless otherwise noted.

70 °C.

50 °C.

95 °C, 10 days, only from the E isomer of starting material. The yield is determined by ¹⁹F NMR.