Table 5.
Baseline characteristics of the severe sepsis cohort
| Characteristics | Alive n = 954 | Deceased n = 237 | p value |
|---|---|---|---|
| Age, median years (IQR) | 55 (44–68) | 63 (53–73) | <0.001 |
| Male sex n (%) | 522 (54.7) | 129 (54.4) | 0.94 |
| Diabetes n (%) | 243 (25.5) | 51 (21.5) | 0.20 |
| Immunosuppressed n (%) | 281 (29.5) | 99 (41.8) | <0.001 |
| Hypertension n (%) | 384 (40.3) | 81 (34.2) | 0.18 |
| Solid tumor with mets n (%) | 85 (8.9) | 75 (31.6) | <0.001 |
| Chemotherapy in past 4 weeks n (%) | 159 (16.7) | 74 (31.2) | <0.001 |
| Oncology patient n (%) | 259 (27.1) | 132 (55.7) | <0.001 |
| Active tobacco use n (%) | 65 (6.8) | 23 (9.7) | 0.07 |
| Creatinine clearance, median ml/min (IQR) | 62.7 (33.2–93.9) | 46.1 (30.9–75.8) | <0.001 |
| ED APACHE II score, IQR | 14 (10–19) | 18 (13–23.5) | <0.001 |
| ED SOFA score, IQR | 3 (2–5) | 4 (3–7) | <0.001 |
IQR interquartile range, ED emergency department, APACHE II acute physiology and chronic health evaluation II, SOFA sequential organ failure assessment