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. 2020 Feb 27;10(5):766–788. doi: 10.1016/j.apsb.2020.02.008

Table 3.

Potential 3CLpro inhibitors from ZINC drug database.

No. Drug name Structure Pharmacological functions
1 Lymecycline Image 44 Anti-bacterial effect
2 Chlorhexidine Image 45 Anti-bacterial effect
3 Alfuzosin Image 46 Anti-hypertensive agent, benign prostatic hyperplasia
4 Cilastatin Image 47 Renal peptidase inhibition
5 Famotidine Image 48 Anti-ulcerative activity
6 Almitrine Image 49 Treatment of cognitive and chronic sensory nerve impairment
7 Progabide Image 50 Anti-epileptic effect
8 Nepafenac Image 51 Treatment of pain and inflammation associated with cataract surgery
9 Carvedilol Image 52 Vasodilator effect
10 Amprenavir Image 53 HIV-1 protease inhibition
11 Tigecycline Image 54 Anti-bacterial effect
12 Demeclocycline Image 55 Anti-bacterial effect
13 Montelukast Image 56 Anti-allergic, anti-asthmatic effects
14 Carminic acid Image 57 Food additive
15 Mimosine Image 58 Depilatory effect
16 Flavin mononucleotide Image 59 Electron transference in biological oxidation
17 Lutein Image 60 Vision protection,
anti-oxidation
18 Cefpiramide Image 61 Anti-bacterial effect
19 Phenethicillin Image 62 Anti-bacterial effect
20 Candoxatril Image 63 Anti-hypertensive effect
21 Nicardipine Image 64 Anti-hypertensive effect
22 Estradiol valerate Image 65 Treatment of estrogen deficiency
23 Pioglitazone Image 66 Anti-diabetic effect
24 Conivaptan Image 67 Treatment of hyponatremia
25 Telmisartan Image 68 Anti-hypertensive effect
26 Doxycycline Image 69 Anti-bacterial effect
27 Oxytetracycline Image 70 Anti-bacterial effect