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. 2020 Mar 9;181(2):281–292.e6. doi: 10.1016/j.cell.2020.02.058

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Figure S1 — Cryo-EM Data Processing and Validation, Related to Figures 3, 4, and 5

A-B. Representative electron micrograph (A) and class averages (B) of SARS-CoV-2 S embedded in vitreous ice. Scale bar: 100nm. C. Gold-standard Fourier shell correlation curves for the closed (blue) and partially open trimers (red). The 0.143 cutoff is indicated by horizontal dashed lines. D-E. Local resolution map calculated using cryoSPARC for the closed (D) and partially open (E) reconstructions.