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. 2020 Feb 21;58(3):155–168. doi: 10.1016/j.resinv.2019.12.005

Fig. 4.

Fig. 4

A: Time course of the cAMP concentration in ASL (m) or basolateral supernatant (s) of uninfected HNE cells treated with formoterol (FRM, 100 nM) or vehicle (Veh) collected before and at 24 h and 72 h after pretreatment. B: Viral titers in ASL from HNE cell cultures pretreated with cAMP (10 μM or 100 μM) or vehicle (Veh) collected between 24 h and 72 h after infection. C and D: The CD13 mRNA (C) and protein concentrations in the ASL (D) of uninfected HNE cells pretreated with cAMP (10 μM or 100 μM) or vehicle (Veh) for 72 h. E: The fluorescence intensity of acidic endosomes in HNE cells at 72 h after pretreatment with cAMP (10 μM or 100 μM) or vehicle (Veh). The mean value of the fluorescence intensity of the vehicle-treated cells was set to 100%. A–E: The results are presented as the mean ± SEM of four (A, C-E) or five (B) subjects. Significant differences compared with cells pretreated with vehicle are indicated by *p < 0.05, **p < 0.01, and ***p < 0.001.