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. 2020 Jan 21;39(4):379–388. doi: 10.1016/j.healun.2019.12.009

Figure 1.

Figure 1

Abs to lung-associated SAgs in LTxRs diagnosed with RVI and stable LTxRs. Serum samples collected from LTxRs diagnosed with RVI (n = 35) and from stable LTxRs (n = 32) were used to measure Abs to lung-associated SAgs (Col-V and Kα1T). Abs to Col-V (78.3 ± 25.1 vs 54.9 ± 15.1, p = 0.0169) and Kα1T (74.7 ± 20.6 vs 43.3 ± 17.2, p = 0.0145) were significantly higher in LTxRs with RVI compared with stable LTxRs. Further, Abs to kidney-associated antigen Col-IV were not significantly different between stable LTxRs and LTxRs with RVI (14.2 ± 8 vs 15.6 ± 6.7, p = 0.248). The antibody development to lung SAgs was compared between the stable and RVI LTxR using Mann–Whitney test. Asterisk indicates statistically significant. Ab, antibody; Col-IV, collagen-IV; Col-V, collagen-V; Kα1T, K-alpha-1 tubulin; LTxR, lung transplant recipient; RVI, respiratory viral infection; SAg, self-antigen.