Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic of mivaRNA biogenesis. VA RNA is transcribed from the viral genome by cellular polymerase (pol) III and is transported to the cytoplasm by Exp5. There, VA RNA binds Dicer and is processed to mivaRNAs able to bind Ago and regulate the expression of target genes. VA RNA is expressed to high levels and saturates Exp5, Dicer and Ago.
