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. 2014 Apr 3;5:91–97. doi: 10.1016/j.coviro.2014.03.001

Figure 2.

Figure 2

The T-cell immunogenic variation of H7N9 as compared with 2009 pH1N1. The previously well-defined antigenic epitopes of influenza virus (colored squares) are distributed in all of the major proteins (gray stripes, 10 well-defined proteins as illustrated herein) of the virus. The peptides have different HLA-restrictions (yellow for HLA-A2, pink for HLA-A24, green for HLA-A1, and cyan for HLA alleles from A3 supertype), which may cover a large majority of the population. The peptides with mutated sites when compared between H7N9 and 2009 pH1N1 are marked with a bias line in the square.