Table 4.
Analysis of Factors Affecting IFD in BSI Patients with HM
| Risk Factor | N (n=1033) | IFD (n=116) | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |||
| Age >45 years | 362 (35.0%) | 50 (43.1%) | 1.469 (1.093–2.174) | 0.043 | 1.531 (1.007–2.327) | 0.046 |
| Renal inadequacy | 104 (10.1%) | 20 (17.2%) | 2.066 (1.214–3.515) | 0.006 | 1.229 (0.678–2.228) | 0.497 |
| Charlson Comorbidity index >3 | 132 (12.8%) | 25 (21.6%) | 2.080 (1.279–3.382) | 0.003 | 1.159 (0.665–2.021) | 0.603 |
| Pitt bacteremia score >3 | 236 (22.8%) | 41 (35.3%) | 2.024 (1.340–3.057) | 0.001 | 1.264 (0.781–2.046) | 0.236 |
| Profound neutropenia | 851 (82.3%) | 105 (90.5%) | 2.188 (1.150–4.162) | 0.015 | 1.734 (0.877–3.429) | 0.041 |
| Use of vasopressors | 214 (20.7%) | 41 (35.5%) | 2.351 (1.552–3.561) | 0.000 | 1.701 (1.032–2.804) | 0.032 |
| Hb <55g/L | 421 (40.7%) | 61 (52.6%) | 1.716 (1.164–2.529) | 0.006 | 1.266 (0.829–1.933) | 0.254 |
| ALB <30g/L | 546 (52.9%) | 81 (69.8%) | 2.250 (1.482–3.414) | 0.000 | 1.625 (1.036–2.551) | 0.047 |
| ALT ≥60U/L | 345 (33.4%) | 53 (45.7%) | 1.801 (1.218–2.662) | 0.003 | 1.379 (0.909–2.093) | 0.072 |
| APTT ≥43sec | 367 (35.5%) | 53 (45.7%) | 1.616 (1.094–2.386) | 0.015 | 1.169 (0.77–1.776) | 0.396 |