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. 2020 Mar 24;14:1209–1218. doi: 10.2147/DDDT.S227892

Figure 2.

Figure 2

Miconazole stimulates noncanonical p62-KEAP1 pathway in bladder cancer cells. (A and B; upper panels) T24 and 5637 BC cells were treated with increased concentrations of miconazole for 24 h, total proteins were extracted and expression levels of p62 and KEAP1 were detected by Western blot. (A and B; lower panels) The relative band intensities of proteins presented in (A and B) were quantitated by densitometric scanning and are presented as the fold of control group; and the statistical calculation from blots more than three independent experiments are shown (n=4). The results are presented as the means ± S.D. *P<0.05 compared with Con. group.