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. 2020 Mar 24;13:2469–2481. doi: 10.2147/OTT.S240081

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© 2020 Wang et al.

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Effect of IL-6/STAT3 signaling pathway suppression on U87 cells apoptosis, invasion, and migration. (A and B) Flow cytometry assays for cell apoptosis in different cell groups. (C and E) Invasive ability of different cell groups (transwell assay). (D and F) Migrational ability of different cell groups (transwell assay). Control shRNA, Negative Control; Bit1 shRNA, lentivirus containing the cDNA sequence of Bit1; sh, short hairpin; Corylifol A. Inhibits IL-6-induced STAT3 activation and phosphorylation. **P < 0.01, ***P < 0.001.