Table 1. Demographic Summaries.

	All Participants (n=67)	Randomization Group
		Placebo (n = 34)	Vortioxetine (n=33)	p-value
Age (Years) - Mean (SD)	40.0 (13.1)	39.8 (13.2)	40.3 (13.2)	0.89
Age at Onset (Years) – Mean (SD), missing n=6	24.1 (13.7)	18.7 (9.8)	29.4 (14.9)	0.002
Body Mass Index (kg/m2) – Mean (SD)	37.9 (8.8)	36.5 (7.9)	39.3 (9.6)	0.20
Days of Binge Eating per Week at Baseline – Mean (SD)	4.3 (1.5)	4.3 (1.6)	4.4 (1.5)	0.74
Sex – n (%)				0.86
Female	45 (67.2%)	22 (64.7%)	23 (69.7%)
Male	22 (32.8%)	12 (35.3%)	10 (30.3%)
Race – n (%)				0.18
African American	36 (53.7%)	16 (47.1%)	20 (60.6%)
Caucasian	15 (22.4%)	6 (17.7%)	9 (27.3%)
Hispanic/Latino	12 (17.9%)	8 (23.5%)	4 (12.1%)
Asian	2 (3.0%)	2 (5.9%)	0 (0.0%)
Multiple Races	2 (3.0%)	2 (5.9%)	0 (0.0%)
Education – n (%)				0.40
Less than high school	3 (4.5%)	1 (2.9%)	2 (6.1%)
Graduated high school/GED	11 (16.4%)	3 (8.8%)	8 (24.2%)
Some college	25 (37.3%)	13 (38.2%)	12 (36.4%)
College graduate	17 (25.4%)	11 (32.4%)	6 (18.2%)
Post graduate (College +)	11 (16.4%)	6 (17.7%)	5 (15.2%)
Marital Status – n (%)				0.23
Single	47 (70.2%)	26 (76.5%)	21 (63.6%)
Married	9 (13.4%)	2 (2.9%)	7 (21.2%)
Divorced/separated	9 (13.4%)	5 (14.7%)	4 (12.1%)
Living together/engaged	1 (1.5%)	1 (2.9%)	0 (0.0%)
Widowed	1 (1.5%)	0 (0.0%)	1 (3.0%)
Employment Status – n (%)				0.38
Employed full time	21 (31.3%)	12 (35.3%)	9 (27.3%)
Employed part time	15 (22.4%)	8 (23.5%)	7 (21.2%)
Student	5 (7.5%)	4 (11.8%)	1 (3.0%)
Retired	2 (3.0%)	0 (0.0%)	2 (6.1%)
Unemployed	23 (34.3%)	10 (29.4%)	13 (39.4%)
Other	1 (1.5%)	0 (0.0%)	1 (3.0%)
Current health conditions (yes) – n (%)
High blood pressure	16 (25.0%)	9 (29.0%)	7 (21.2%)	0.67
High cholesterol	5 (7.8%)	1 (3.2%)	4 (12.1%)	0.36
Diabetes	6 (9.4%)	3 (9.7%)	3 (9.1%)	1.00