Skip to main content
. Author manuscript; available in PMC: 2020 Apr 25.
Published in final edited form as: Lab Invest. 2019 Oct 25;100(4):630–642. doi: 10.1038/s41374-019-0338-2

Fig. 2. Shp2 deletion in corneal basal epithelial cells reduced nerve innervation density in corneal epithelium.

Fig. 2.

(A, B) Representative whole mount overviews of mouse corneal epithelial nerve innervation from adult mice administered Dox for 10 days. (C-F) Detail structure of central corneal nerve networks. Note that Shp2 deficiency resulted in lower density of corneal epithelial nerve fibers/bundles (compare D to C; F to E). In addition. Three mice (N= 6 corneas) of each group were examined. Shp2 deficiency caused less nerve fibers in corneal epithelial nerve networks (compare F to E).