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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Lab Invest. 2019 Dec 19;100(4):516–526. doi: 10.1038/s41374-019-0354-2

Figure 2.

Figure 2.

BALB/c-KitW-sh/W-sh mice have enlarged spleens and minor hematologic abnormalities. A. Red blood cell indices in peripheral blood samples were measured by automated analysis. B. Differential cell counts were determined by flow cytometry for neutrophils (GR1+), T cells (CD3+), B cells (B220+), monocytes (F4/80+), eosinophils (CCR3+) and basophils (CD49b+FcεRIα+). C. Spleen weights. D. Megakaryocyte counts from spleen sections. E. Sections of spleen showing increased hematopoiesis and numerous megakaryocytes (solid arrowheads) in spleen section from the BALB/c-KitW-sh/W-sh mouse. A-D. N=7–10 mice per group, combined from 2 independent experiments. Lines represent mean values ± s.e.m. Scale bars in E indicate 100 μm.