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. Author manuscript; available in PMC: 2020 Sep 25.
Published in final edited form as: Neuron. 2019 Jul 16;103(6):1056–1072.e6. doi: 10.1016/j.neuron.2019.06.013

Figure 2. DA deficiency reduces ChI pacemaking.

Figure 2

A) Cell-attached recording (left) and a fluorescent ChI (right). Bar, 10 μm. B) Representative traces of whole-cell recordings from ChIs. C) The firing frequency is lower in ChIs from Slc6a3DTR/+ mice examined 2 and 4 wk after treatment with dT. Box-and-whisker plots: boundary, 25th and 75th percentiles; median, solid black line; mean, solid red; whiskers, 10th and 90th percentiles; outlying points, red circles. n= cells. D) The plot shows a higher CV in ChIs from DATdT mice. E) Plots show a negative correlation between the CV and the firing rate of ChIs from control, F) reserpine, and G) DATdT mice. Lines, linear regression. See also Figure S2 and Table S2.