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. 2020 Feb 13;48(6):3366–3378. doi: 10.1093/nar/gkaa083

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Atomic details of the interaction between TetR and RNA aptamer. (A) Close-up view of the TetR-aptamer interface. (B) Stick representation of the trans sugar-edge/sugar-edge base pairing between nucleobases G12 and G31 (in yellow) and interacting amino acids Arg28 (blue) and Arg28′ (gray). (C) Interaction between Arg28 (blue) and its interaction partners: A15, A30 and G31, (D) between Tyr42′, Lys46′ (gray), G8 and G33, (E) between Gln38 (blue), A15 and G17 and (F) between Tyr42 (blue) and U16. In all panels, dotted lines indicate hydrogen bonds (black) and cation–π or π–π-stacking interactions (red).