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. 2020 Feb 27;48(6):2853–2865. doi: 10.1093/nar/gkaa126

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — SMN protein expression in mouse peripheral tissues after SC injection of MOE10-29 or PMO10-29. Western blotting analysis of SMN levels in mouse liver (A andB), heart (C andD), kidney (E andF) and muscle (G andH) tissues at three time points (P7, P15 and P30) after the treatments described in Figure 1 (n = 4). (*) P < 0.05 high dose versus low dose of the same ASO; (^#) P < 0.05 MOE versus PMO at the same dose.