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. 2020 Feb 27;48(6):2853–2865. doi: 10.1093/nar/gkaa126

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — SMN protein expression in mouse CNS tissues after SC injection of MOE10-29 and PMO10-29. Western blotting analysis of SMN levels in mouse spinal cord (A and B) and brain (C and D) tissues at three time points (P7, P15 and P30) after treatment as in Figure 1 (n = 4). (*) P < 0.05 high dose versus low dose of the same ASO; (^#) P < 0.05 MOE versus PMO at the same dose.