Table 3.

Risk factors for 30-day mortality^a

Characteristic	Univariate analysis (n = 2720)			Multi-variate analysisb (n = 2430c)
	OR	95% CI	p value	OR	95% CI	p value
Demography
Sex (female)	1.11	0.91–1.36	0.30	1.28	1.00–1.64	0.05
Age	1.04	1.03–1.05	< 0.001
Severity of disease
SAPS3 (per unit increase)	1.07	1.06–1.08	< 0.0001
tSAPS3 (per unit increase)	1.07	1.06–1.08	< 0.0001	1.06	1.05–1.07	< 0.001
Body temperature, per °C increase	0.78	0.75–0.82	< 0.001	0.82	0.77–0.87	< 0.001
Quality of care
1 h sepsis bundle achieved	1.06	0.89–1.28	0.51
Incorrect AB	1.50	1.06–2.12	0.02	1.73	1.13–2.65	0.01
Treatment limitations
At 48 h	10.30	8.42–12.62	< 0.001	8.06	6.42–10.12	< 0.001

AB antibiotic, ED emergency department, ICU Intensive Care Unit, SAPS3 Simplified Acute Physiology Score 3, tSAPS3 SAPS3 minus points for temperature component of score, treatment limitations: any treatment limitations ordered within 48 h of admittance ^aestimated by GEE logistic regression ^badjusted for all variables in the column. ^cMinus 290 patients who lacked information on body temperature