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. 2020 Mar 16;180(3):725–733. doi: 10.1007/s10549-020-05589-3

Table 2.

Overview of decrease in ALND rates for subgroups based on ypN status for both cN0 and cN + patients (all patients of the cohort were included in this analysis)

Year of diagnosis 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016
cN0 patients, n 164 138 191 185 303 523 610 831 943 1280 662
ALND rate in:
 ypN0, % (absolute numbers) 78.3 (65/83) 69.7 (62/89) 63.2 (67/106) 44.2 (42/95) 31.9 (59/185) 13.1 (37/282) 6.1 (22/359) 3.8 (20/520) 3 (19/626) 2.4 (22/927) 1.2 (6/512)
 ypN+ , % (absolute numbers) 100 (81/81) 95.9 (47/49) 91.8 (78/85) 92.2 (83/90) 88.1 (104/118) 75.9 (183/241) 61.8 (155/251) 50.5 (157/311) 31.2 (99/317) 24.6 (87/353) 22.7 (34/150)
Year of diagnosis 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016
cN + patients, n 302 363 456 487 487 606 608 744 806 1120 652
ALND rate in:
 ypN0, % (absolute numbers) 98.2 (55/56) 98.8 (85/86) 100 (103/103) 100 (82/82) 93.6 (102/109 92.1 (116/126 94 (125/133) 80 (133/166) 65.9 (116/176) 45.2 (109/241) 41.9 (49/117)
 ypN+ , % (absolute numbers) 99.6 (245/246) 99.6 (276/277) 100 (353/353) 99.8 (404/405) 100 (378/378) 97.9 (470/480) 97.3 (462/475) 93.6 (541/578) 84.9 (535/630) 61.7 (542/879) 55.5 (297/535)