Table 1.
Comparison of baseline characteristics of colorectal cancer between training cohort and validation cohort.
| Characteristic | Training cohort (n = 635) | Validation cohort (n = 617) | P value |
|---|---|---|---|
| Age at diagnosisa (years) | 59 (18-75) | 59 (26-75) | 0.492 |
| Gender | 0.962 | ||
| Male | 347 (54.6) | 338 (54.8) | |
| Female | 288 (45.4) | 279 (45.2) | |
| Race | 0.356 | ||
| White | 502 (79.1) | 467 (75.7) | |
| Black | 69 (10.9) | 76 (12.3) | |
| Other | 64 (10.1) | 74 (12.0) | |
| Tumor location | 0.184 | ||
| Rectum | 122 (19.2) | 120 (19.4) | |
| Left colon | 273 (43.0) | 293 (47.5) | |
| Right colon | 240 (37.8) | 204 (33.1) | |
| Differentiation degree | 0.170 | ||
| Well/moderately differentiated | 473 (74.5) | 480 (77.8) | |
| Poorly differentiated/undifferentiated | 162 (25.5) | 137 (22.2) | |
| Pathological types | 0.799 | ||
| Adenocarcinoma | 585 (92.1) | 566 (91.7) | |
| Mucinous adenocarcinoma/signet-ring cell carcinoma | 50 (7.9) | 51 (8.3) | |
| Tumor size (cm) | 0.355 | ||
| <5 | 350 (55.1) | 324 (52.5) | |
| ≥5 | 285 (44.9) | 293 (47.5) | |
| T stage | 0.193 | ||
| T1/T2 | 34 (5.4) | 44 (7.1) | |
| T3/T4 | 601 (94.6) | 573 (92.9) | |
| The number of LNMs | 0.146 | ||
| 0 | 166 (26.1) | 191 (31.0) | |
| 1-3 | 236 (37.2) | 222 (36.0) | |
| ≥4 | 233 (36.7) | 204 (33.1) | |
| M stage | 0.161 | ||
| M0 | 400 (63.0) | 412 (66.8) | |
| M1 | 235 (37.0) | 205 (33.2) | |
| CEA level (U/ml) | 0.510 | ||
| <5 | 258 (40.6) | 262 (42.5) | |
| ≥5 | 377 (59.4) | 355 (57.5) | |
| PNI status | 0.790 | ||
| No | 434 (68.3) | 426 (69.0) | |
| Yes | 201 (31.7) | 191 (31.0) | |
| TD counta | 2 (1-24) | 2 (1-38) | 0.255 |
aExcept these, other values were summarized as frequencies and percentages. CEA: carcinoembryonic antigen; PNI: perineural invasion; TD: tumor deposit.