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. Author manuscript; available in PMC: 2020 Mar 29.
Published in final edited form as: Gynecol Oncol. 2019 Dec 13;156(2):423–429. doi: 10.1016/j.ygyno.2019.12.003

Table 4.

Associations of each prognostic factors including EZH2 expression in primary tumor tissue with PFS.

Characteristic Hazard ratio 95% CI P-valuea
Age: high(>median) vs low(≤median) 2.422 0.789 to 8.942 0.1283
bmi: high(>median) vs low(≤median) 0.788 0.254 to 2.374 0.6683
EZH2 mRNA: high(>median) vs low(≤median) 0.59 0.178 to 1.769 0.3611
EZH2 protein (WB): negative vs positive 0.307 0.047 to 1.143 0.117
Stage: I/II vs III/IV 0.968 0.321 to 3.008 0.9534
Tumor grade: 1/2 vs 3 0.674 0.206 to3.005 0.5458
Tumor penetration: inner half vs outer half/serosa 0.752 0.242 to 2.263 0.6066
Cytology: negative vs positive/suspicious 1.153 0.297 to 7.562 0.8556
Nodal status: negative vs positive 0.664 0.201 to 2.538 0.5118
Vascular invasion: absent vs present 0.4 0.129 to 1.207 0.089
a

Score test from univariate Cox PH model except p-values for EZH2 expressions resulting from Monte-Carlo permutation-based log-rank tests.