Table 3.
Fold changes of genes that were differentially expressed across four post-exposure time-points in CBNP exposed versus control mice.
| Gene name | Gene symbol | 3 h | 1 d | 2 d | 3 d | 4 d | 5 d | 14 d | 42 d |
|---|---|---|---|---|---|---|---|---|---|
| Amiloride binding protein 1 | Abp1 | − 1.7 | – | − 1.9 | 1.8 | − 1.6 | – | – | – |
| Angiopoietin-like 4 | Angptl4 | 5.2 | − 2.1 | 1.7 | – | 2.2 | – | – | – |
| Asialoglycoprotein receptor 1 | Asgr1 | – | − 2.2 | − 1.8 | – | − 1.8 | – | − 2.2 | – |
| Cathepsin K | Ctsk | – | – | 1.9 | 2.0 | – | – | 2.6 | 2.5 |
| Cell adhesion molecule with homology to L1CAM | Chl1 | – | 1.5 | 1.6 | 1.6 | – | – | – | 1.5 |
| Ceruloplasmin | Cp | 1.5 | – | 1.9 | 1.7 | – | – | – | 1.5 |
| Chemokine (C-C motif) receptor-like 1 | Ccrl1 | − 2.0 | − 1.9 | − 1.6 | − 1.8 | – | – | – | – |
| Complement component 3 | C3 | – | 1.5 | 1.6 | – | – | – | 1.8 | 1.8 |
| C-type lectin domain family 4, member d | Clec4d | – | 1.9 | 1.9 | – | – | – | 2.1 | 2.4 |
| Cytidine 5′-triphosphate synthase | Ctps | 1.9 | 1.9 | 1.6 | – | – | – | 1.5 | – |
| Cytochrome P450, family 2, subfamily a, polypeptide 4 | Cyp2a4 | – | – | − 1.9 | – | − 2.3 | − 2.3 | − 2.2 | – |
| Eosinophil-associated, ribonuclease A family, member 6 | Ear6 | – | – | 1.6 | 1.7 | – | – | 2.3 | 1.7 |
| Glycoprotein (transmembrane) nmb | Gpnmb | – | – | 2.0 | 2.0 | – | – | 2.3 | 3.4 |
| Growth differentiation factor 15 | Gdf15 | 1.7 | – | 1.6 | – | – | – | 1.7 | 1.9 |
| Hemopexin | Hpx | 2.7 | 2.6 | 1.9 | – | – | – | 1.6 | – |
| Immunoresponsive gene 1 | Irg1 | – | 1.9 | 3.2 | – | – | – | 1.8 | 2.7 |
| Inter alpha-trypsin inhibitor, heavy chain 4 | Itih4 | – | 1.5 | – | 1.7 | – | – | 1.9 | 2.4 |
| Interleukin 1 receptor, type II | Il1r2 | 2.7 | 2.0 | 1.5 | – | – | – | 1.6 | – |
| Interleukin 4 induced 1 | Il4i1 | – | 1.6 | 1.7 | – | – | – | 2.0 | 2.2 |
| LincRNA:chr1:134867906-134885481_R | – | 1.8 | – | – | – | – | 1.6 | 1.8 | 2.6 |
| LincRNA:chr10:93774693-93893616_F | – | − 1.5 | – | − 1.7 | − 1.5 | – | 1.6 | – | – |
| LincRNA:chr12:5303823-5379098_R | – | 1.9 | − 1.7 | – | – | – | 1.7 | 1.9 | – |
| LincRNA:chr18:35967933-35986564_F | – | 1.7 | – | – | – | – | 1.8 | 1.9 | 1.8 |
| LincRNA:chr18:63525907-63526504_R | – | − 1.5 | – | − 1.8 | – | – | − 1.6 | − 1.5 | – |
| LincRNA:chr8:80581177-80621652_F | – | 1.6 | – | – | – | – | 1.5 | 1.6 | 1.5 |
| Mab-21-like 3 (C. elegans) | Mab21l3 | – | 1.6 | 1.9 | – | – | – | 1.8 | 2.0 |
| Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Nfkbia | 2.8 | – | – | – | – | 1.5 | 1.5 | 1.6 |
| Palmdelphin | Palmd | − 1.8 | – | − 1.7 | − 1.6 | – | 1.5 | – | – |
| Predicted gene 3161 | Gm3161 | − 1.6 | – | – | 1.6 | – | − 1.6 | – | − 1.5 |
| Protein Z, vitamin K-dependent plasma glycoprotein | Proz | 1.6 | 1.8 | – | – | – | – | 2.2 | 3.6 |
| Serine peptidase inhibitor, Kazal type 5 | Spink5 | 1.5 | 2.0 | – | 1.5 | – | – | 1.8 | – |
| Solute carrier family 26, member 4 | Slc26a4 | – | – | 2.3 | 3.0 | – | – | 9.3 | 8.2 |
| Tumor necrosis factor receptor superfamily, member 9 | Tnfrsf9 | – | 1.7 | – | 1.7 | – | – | 1.6 | 1.6 |
| Vanin 1 | Vnn1 | – | 1.9 | – | 1.6 | – | – | 2.9 | 2.3 |
| Vanin 3 | Vnn3 | – | 2.2 | – | 1.6 | – | – | 2.3 | 1.7 |
All genes had p < 0.05; “–” indicates that gene in that specific time-point did not pass the selection criteria. h — hour; d — day.