Table 5.
Suggested Efficacy of Different Anthelmintic Drugs Tested Against Baylisascaris schroederi
| Anthelmintics | Formulation | Dosage | Effectb | Referencesc |
|---|---|---|---|---|
| Albendazolea | Oral | 6 mg/kg, once | Negative of eggs in faecal floatation examination after 9 days of treatment | Liu and Yang (1994) |
| Doramectina | Pour on | 0.5 mg/kg, once | n/a | CCRCGP (unpublished data) |
| Febantel | Oral | 20 mg/kg, once | Reported as effective without supporting data | Wu and Hu (1985b) |
| Fenbendazolea | Oral | 5 mg/kg, once | n/a | CCRCGP (unpublished data) |
| Levamisole | Oral | 7–8 mg/kg per 2 months, four times | Negative of worm or eggs in faecal examination after four times of treatment | Wu and Hu (1988) |
| Oral/in feed | 5–10 mg/kg, once | Negative of worm in faecal examination after 4 days of treatment | Ye and Zhang (1981) | |
| Unknown | 8–10 mg/kg per 2 weeks | Reported as effective without supporting data | Qiu (1990) | |
| Mebendazolea | Unknown | 3.2–6.4 mg/kg | Reported as effective without supporting data | Qiu (1990) |
| Methylimidazole compound | Unknown | Unknown | Reported as effective without supporting data | Zhang and Zhang (2002) |
| Milbemycina | 0.5 mg/kg, once | n/a | CCRCGP (unpublished data) | |
| Ivermectina | Usually oral | 0.2 mg/kg per day, twice | None reduction of egg counts in faecal flotation examination after 10–15 days of treatment (without negative control) | Li et al. (2015) |
| Pyrantel pamoatea | Oral | 10 mg/kg per day, twice | 80.0% (ointment) reduction of egg counts in faecal floatation examination after 10–15 days of treatment | Li et al. (2015) |
| Piperazine citrate | Oral | 150 mg/kg, once | Significant reduction of worms in faecal examination after 5 days of treatment | Ye and Zhang (1981) |
| Unknown | 140–160 mg/kg per 2 weeks | Reported as effective without supporting data | Qiu (1990) | |
| Selamectina | Spot-on | 6–12 mg/kg, once | n/a | CCRCGP (unpublished data) |
| Trichlorfon | Unknown | 55 mg/kg | Negative of worm in faecal examination after 5 days of treatment; significant side effect was observed | Ye and Zhang (1981) |
a
Anthelmintics used in practice currently.
b
None of these studies followed International Harmonisation of Anthelmintic Efficacy Guidelines (Vercruysse et al., 2001, Vercruysse et al., 2002); n/a, not available.
c
CCRCGP, China Conservation and Research Centre for the Giant Panda; CRBGP, Chengdu Research Base of Giant Panda.