Table 2.
Classification of endometrial biopsy and potential effect on fertility (adapted from Powers et al. [26])
Categories | Characteristics | Effect on fertility | Prognosis |
---|---|---|---|
Grade 1A | Normal endometrium | Normal | Very good |
Grade 1B | Few lymphocytes within the endometrium. Siderophages (postpartum or postabortion). Low-grade infection, inflammation due to mating | Slightly decreased | Good if treated promptly |
Grades 2A and 2B | Active and acute, chronic, or chronic active endometritis. Chronic inflammation is more deeply located in the endometrium, compared with active and chronic active inflammation | Reduced conception rate, increased early embryo death | Good if recent, poor if the female has been barren for >1 year |
Grade 3A | Chronic endometritis with glandular fibrosis | Increased early embryonic loss or abortion | Poor |
Grade 3B | Uterine neoplasia | Poor |