Table 1.
Comparative phenotype and tissue localisation of porcine DC subsets and related antigen presenting cells
| CD172a | CD1 | CD4 | CD11R1 | CD14 | CD16 | MHCII | CD80/86 | References | |
|---|---|---|---|---|---|---|---|---|---|
| MoDC | + | + | − | − | +/low | + | + | + | [23], [24] |
| GM-CSF BMDC | + | + | − | − | + | + | + | + | [23] |
| Flt3L BMDC | + | + | − | − | +/−a | + | + | + | unpublished |
| blood cDC | low | +/−b | − | − | − | +/−b | high | + | [40] |
| pDC | low/−c | +/−b | + | − | − | +/−b | + | low | [40] |
| thyroid gland DC | + | n.d.d | n.d. | n.d. | n.d. | n.d. | + | n.d. | [78] |
| thymus DC | + | + | n.d. | n.d. | n.d. | n.d. | + | n.d. | [77] |
| skin DC | + | + | n.d. | n.d. | ± | n.d. | + | + | [62] |
| mucosal tissue DC | +/−e | −f | n.d. | +/−e | −f | + | + | + | [46], [47], [61] |
| mucosal lymph DC | +/−g | +/− | n.d. | + | n.d. | +/−g | + | + | [47] |
| monocytes | + | − | − | − | + | + | +/− | low | [40], [44] |
| macrophages | + | +/− | − | − | +/− | + | low | low | [118], [119] |
| fibrocytes | + | + | n.d. | n.d. | + | + | + | + | [25] |
a
Two subsets.
b
Variable, two subsets with some animals (see also Fig. 1).
c
Can be negative in mucosal tissue [55].
d
Not determined.
e
Four subsets based on CD172a/CD11RI expression and dependent on localization in LP, PP and MLN [47].
f
Negative on LP DC [46].
g
Two subsets: CD172a+CD1+CD16+ and CD172a−CD1−CD16−.