Table 7.

Mannosylated nanoparticle/microparticle-based vaccine enhancing targeting of the immune system.

Delivery vehicle	Vaccine antigen	Reference
Mannosylated anionic poly(varepsilon-caprolactone)-poly(ethyleneglycol)-poly(varepsilon-caprolactone)	Human basic fibroblast growth factor	[231]
Mannosylated cationic liposomes: N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTMA)/cholesten-5-yloxy-N-(4-((1-imino-2-d-thiomannosyl-ethyl)amino)butyl)formamide (Man-C4-Chol)/Chol	DNA vaccine	[232]
Mannosylated cationic liposomes: cholesten-5-yloxy-N-{4-[(1-imino-2-d-thiomannosylethyl)amino]butyl-formamide (Man-C4-Chol) with cationic lipid	Ovalbumin	[233]
Mannosylated cationic nanoparticles: emulsifying wax plus CTAB cationic surfactant; mannosylation of nanoparticles with or without entrapped endosomolytic agents, dioleoyl phosphatidylethanolamine (DOPE) and cholesterol	DNA vaccine	[234]