Table 2.
Likely binding region of human Abs
| ELISA reactivitya | Group designationb | Number of Absc | Number neutralizingd | Likely binding regione |
|---|---|---|---|---|
| All S1-IgG fragments | 1A | 13 | 9 | 318–510 |
| 12–672 | 3A | 1 | 0 | 510–672 |
| 12–672, 12–510 | 2A | 4 | 1 | 12–261 |
| 12–672, 12–510, 318–510 | 1B | 45 | 14 | 318–510 |
| 12–672, 261–672 | 3B | 2 | 0 | 510–672 |
| 12–510 | 2B | 29 | 2 | 12–261 |
| 12–510, 318–510 | 1C | 41 | 0 | 318–510 |
| 318–510 | 1D | 29 | 1 | 318–510 |
| Total | 165 | 27 |
a
Fragments with which Abs react.
b
Group designation determined based on likely binding region and fragment reactivity.
c
Number of total Abs that reacted with designated S1-IgG fragments.
d
Number of these Abs that completely neutralized 200TCID50-SARS-CoV (Urbani).
e
Likely binding region of Ab group determined by differential fragment reactivity.