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. 2007 Aug 11;59(12):1277–1289. doi: 10.1016/j.addr.2007.03.021

Table 1.

Host molecules as targets of anti-HCV

Target molecules Reagents References
HMG–CoA reductase Statin [68], [69], [70], [71]
Serine palmitoyltransferase NA255 [81]
Myriocin [82]
IMP dehydrogenase VX-497 [98]
Ribavirin [74], [86]
Mizoribin [74]
MPA [97]
Protein arginin methyltransferase AdoMet, Betaine [102]
α-Glucosidase Deoxynojirimycin [101]
Cyclophilins CsA [27], [28], [29], [30], [31], [32], [33], [34], [35], [36]
NIM811 [27], [33]
DEBIO-025 [34]
HSP90 Geldanamycin, Radicicol [37], [38], [39]
FKBP8 [38]
Unknown PUFAs [70], [103], [108]