. 2006 Oct 19;359(2):264–274. doi: 10.1016/j.virol.2006.09.016

Table 2.

The change in percentage of lymphocyte subsets during immunization of the four B cell epitope peptides of SARS-Cov

Groups	T, B cell subsets (% or ratio)
Groups	CD3⁺(T)	CD3⁻CD19⁺(B)	T/B	CD3⁺CD4⁺(T4)	CD3⁺CD8⁺(T8)	T4/ T8
PBS control	41.88 ± 0.39	51.90 ± 1.31	0.81 ± 0.02	26.18 ± 1.86	13.60 ± 1.68	1.94 ± 0.25
FA control	40. 12 ± 0.31	50.73 ± 0.98	0.80 ± 0.01	24.22 ± 1.33	12.75 ± 1.62	1.96 ± 0.28

MAP 1
14 days	34.16 ± 0.63^a	55.76 ± 0.95^a	0.61 ± 0.01^a	22.43 ± 1.49^b	10.68 ± 0.77^a	2.19 ± 0.16
21 days	33.58 ± 0.64^a	57.58 ± 2.19^a	0.58 ± 0.02^a	23.23 ± 0.67^b	11.56 ± 0.85	1.95 ± 0.24
35 days	43.08 ± 0.71	52.88 ± 0.96	0.814 ± 0.01	25.8 ± 0.59	13.30 ± 1.45	1.96 ± 0.25

MAP 2
14 days	32.28 ± 1.27^a	58.90 ± 1.66^a	0.55 ± 0.03^a	22.44 ± 0.82^b	9.6 ± 0.97^b	2.35 ± 0.21
21 days	34.76 ± 1.21^a	58.02 ± 2.48^a	0.60 ± 0.04^a	22.34 ± 1.03^b	10.66 ± 0.72^b	2.10 ± 0.12
35 days	35.2 ± 1.43^a	54.4 ± 1.91	0.64 ± 0.03^a	20.04 ± 1.39^b	8.83 ± 0.76^a	2.28 ± 0.14

MAP 3
14 days	22.74 ± 0.26^a	43.44 ± 0.67^a	0.52 ± 0.01^a	14.84 ± 1.41^a	7.22 ± 0.36^a	2.09 ± 0.18
21 days	35.22 ± 0.78^a	58.14 ± 1.17^a	0.61 ± 0.01^a	22.20 ± 1.64^b	11.40 ± 0.66^b	1.94 ± 0.06
35 days	40.84 ± 0.71	50.56 ± 0.90	0.81 ± 0.00	24.34 ± 1.98	11.74 ± 0.40	2.07 ± 0.11

MAP 4
14 days	25.60 ± 0.51^a	56.88 ± 1.85^b	0.50 ± 0.01^a	18.32 ± 1.26^a	8.82 ± 0.95^a	2.09 ± 0.25
21 days	34.14 ± 1.75^a	52.70 ± 1.85	0.65 ± 0.02^a	22.90 ± 1.17^b	13.00 ± 0.70	1.772 ± 0.15
35 days	38.14 ± 0.96^a	49.50 ± 3.24	0.77 ± 0.03	22.86 ± 1.17^a	13.68 ± 0.67	1.68 ± 0.14

Lymphocytes were from the mice immunized with the four different peptides on 14 days, 21 days, and 35 days after primary immunization (n = 5). Results are means ± SD.

P value < 0.01 compared with the control group.

P value < 0.05 compared with the control group.