Tabla 5.
Antibiótico | Dosis | Dosis en insuficiencia renal (ml/min) |
---|---|---|
Amikacina | 15-20 mg/kg/24 h | 60-80: 9-12 mg/kg/24 h; 40-60: 6-mg/kg/24 h 30-40: 4,5-mg/kg/24 h; 20-30: 3-4,5 mg/kg/24 h 10-20: 1,5-mg/kg/24 h; < 10: 1-1,5 mg/kg/24 h |
Amoxicilina-clavulánico iv | 2 g/6-8 h | 30-50: 1 g/8 h; 10-30: 500 mg/12 h < 10: 500 mg/24 h |
Amoxicilina-clavulánico vo | 2/0,125 g/12 h | 30-50: 500 mg/8 h; 10-30: 500 mg/12 h < 10: 500 mg/24 h |
Azitromicina iv/vo | 500 mg/24 h | No requiere ajuste |
Cefditoren vo | 400 mg/12 h | 30-50: 200 mg/12 h; < 30: 200 mg/24 h |
Cefepime iv | 2 g/8 h | 30-50: 2 g/12 h; 10-30: 2 g/24 h < 10: 1 g/24 h |
Ceftriaxona iv | 1-2 g/12-24 h | > 10: no requiere; < 10: máximo 2 g/24 h |
Ciprofloxacino iv | 400 mg/12 h | 30-50: no requiere; < 30: 200 mg/12 h |
Ciprofloxacino vo | 500 mg/12 h | 30-50: no requiere; < 30: 250 mg/12 h |
Ertapenem iv | 1 g/24 h | < 30: no utilizar |
Imipenem iv | 1 g/6-8 h | 30-50: 250-500 mg/6-8 h; < 30: 250-500 mg/12 h |
Levofloxacino iv/vo | 500 mg/12-24 h | 20-50: 250 mg/12-24 h; 10-20: 125 mg/12-24 h < 10: 125 mg/24 h |
Linezolid iv/vo | 600 mg/12 h | No requiere ajuste |
Meropenem iv | 1 h/8 h | 30-50: 1 g/12 h; 10-30: 500 mg/12 < 10: 500 mg/24 h |
Moxifloxacino iv/vo | 400 mg/24 h | No requiere ajuste |
Piperacilina/tazobactam iv | 4/0,5 g/6-8 h | 20-50: 2/0,25 g/6 h; < 20: 2/0,25 g/8 h |
Tobramicina iv | 4-7 hg/kg/24 h | 60-80: 4 mg/kg/24 h; 40-60: 3,5 mg/kg/24 h 30-40: 2,5 mg/kg/24 h; 20-30: 2 mg/kg/24 h 10-20: 1,5 mg/kg/24 h |