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. 2005 Jul 1;37(3):420–424. doi: 10.1016/j.bone.2005.04.018

Table 3.

Drug regime for patients whose BMD Z score at the total hip and spine were ≥2

Patient sex/No. Total hip Z score Total spine Z score Drug treatment protocola Cumulative prednisolone equivalent dose (mg) Cumulative ribavirin dose (mg)
M/1 −1.60 −2.59 II 625 19,200
M/2 −2.06 −2.37 I 770 32,400
M/3 −2.09 −1.77 IV 5120 36,000
M/4 −2.18 −1.33 III 2545 28,800
M/5 −2.19 −0.76 IV 8915 14,400
M/6 −2.85 −2.12 I 330 24,000
F/1 −2.05 −1.77 IV 4410 3600
F/2 −2.06 −1.66 III 1885 50,400
F/3 −2.20 −1.86 IV 3010 4800
F/4 −2.43 −3.20 II 3335 12,000
a

I: Oral ribavirin as a loading dose of 2.4 g stat followed by 1.2 g three times daily and prednisolone 0.5–1 mg/kg body weight per day. II: Intravenous ribavirin (400 mg every 8 h) combined with hydrocortisone (100 mg every 8 h). III: Pulses of high-dose methylprednisolone (0.5 g IVI for three consecutive days) added on initial combination therapy. IV: Further pulse of methylprednisolone, up to a total of 3 g.