Figure 3. Stress-relevant concentrations of membrane-impermeable corticosterone infused into the ventral hippocampus of saline pre-treated rats fail to alter accumbal dopamine output relative to vehicle infusions.

A) Saline pre-treated rats receiving ventral hippocampus infusions of BSA-corticosterone conjugate or vehicle (BSA-HBC), with tracing for vehicle + corticosterone infusions from Fig. 2A shown as dotted lines for comparison. Data represent mean ± SEM nA. B) Representative diagrams of carbon paste electrode placements in the medial nucleus accumbens shell and infusion cannula placements in the ventral hippocampus. Figures adapted from Paxinos and Watson (1998). BSA: bovine serum albumin; CORT: Corticosterone; HBC: hydroxypropyl-β-cyclodextrin; VEH: Vehicle.